Benfotiamine
Also called S-benzoylthiamine O-monophosphate
Benfotiamine is a lipid-soluble thiamine derivative that crosses cell membranes more readily than water-soluble thiamine. It has been studied for diabetic neuropathy, vascular health, and advanced glycation end-product inhibition. It is not a better choice for simple energy support, but it is useful for targeted nerve and metabolic applications.
Best for
Nerve health, advanced glycation end-product concerns
Absorption
High
Tolerability
Generally well tolerated
Typical timing
With meals to improve absorption
How to take Benfotiamine
A typical dose of Vitamin B1 (Thiamine): 1–1.5 mg per day (RDA); 100–300 mg for therapeutic use. Best timing: With meals to improve absorption. The form you choose mainly affects absorption and how easily it sits with your stomach, not the overall dose.