Best Supplements for Inflammation
3 evidence-based options for inflammation, summarized from the research: what they do, how to dose them, and how they work together.
Curcumin
Turmeric's anti-inflammatory active compound.
Glucosamine
An amino sugar that supports cartilage and joint comfort.
Omega-3 (Fish Oil)
Anti-inflammatory fats for heart, brain, and joints.
Where to buy for inflammation
Our top options for this goal. Choose third-party-tested brands in the forms each supplement's page recommends.
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Combinations to know
How these supplements pair with each other and beyond.
Curcumin + Omega-3 (Fish Oil)
Complementary anti-inflammatory pathways often combined for joint comfort.
Glucosamine + Omega-3 (Fish Oil)
Omega-3 fatty acids and glucosamine target joint inflammation through complementary pathways and are often combined.
Curcumin + Piperine
Piperine from black pepper can increase curcumin bioavailability dramatically (studies report up to ~20x).
Omega-3 (Fish Oil) + Uridine
DHA from omega-3 is the third component of the classic membrane-building stack with uridine and a choline source.
Collagen + Glucosamine
Collagen and glucosamine target cartilage and joint comfort through different mechanisms and are commonly stacked for joint support.
Citicoline + Omega-3 (Fish Oil)
DHA and a choline source like citicoline are used together to build neuronal membrane phospholipids.
Frequently asked questions
What are the best supplements for inflammation?
The most-researched options are Curcumin, Glucosamine, and Omega-3 (Fish Oil). Each is summarised with its benefits, typical dosing, and the strength of the evidence behind it.
How were these inflammation supplements chosen?
These are the supplements in the Vital Matrix library most commonly used for inflammation, graded by the strength of human evidence. See our methodology for how we grade the research.
Can you combine supplements for inflammation?
Yes, several pair well. For example, Curcumin and Omega-3 (Fish Oil): Complementary anti-inflammatory pathways often combined for joint comfort.