L-Citrulline and Vitamin C
Vitamin C protects nitric oxide from oxidative degradation, extending the vasodilatory effect of citrulline-derived NO.
L-Citrulline
A superior nitric oxide booster that outperforms arginine for pumps and endurance.
Vitamin C
Antioxidant vitamin and iron-absorption amplifier.
Great to combine
These two are frequently stacked together; they complement each other and are commonly taken at the same time.
How to take them
L-Citrulline
- Dose
- 6–8 g citrulline malate (2:1) or 3–4 g pure L-Citrulline, 30–60 min pre-workout
- Timing
- 30–60 minutes before exercise
Vitamin C
- Dose
- 200–1,000 mg per day
- Timing
- With iron-rich meals to maximize iron uptake
Buying L-Citrulline and Vitamin C?
Choose third-party-tested brands in the forms we recommend on each supplement's page.
Some links below are affiliate links: if you buy through them we may earn a small commission at no extra cost to you. It never changes our ratings or evidence grades.
Frequently asked
Can you take L-Citrulline and Vitamin C together?
Yes, they are commonly taken together. Vitamin C protects nitric oxide from oxidative degradation, extending the vasodilatory effect of citrulline-derived NO.
What's the best time to take L-Citrulline and Vitamin C?
Around the same time works well. L-Citrulline: 30–60 minutes before exercise. Vitamin C: With iron-rich meals to maximize iron uptake.
How do L-Citrulline and Vitamin C interact?
Synergy: Work better together than alone. Vitamin C protects nitric oxide from oxidative degradation, extending the vasodilatory effect of citrulline-derived NO.
Related pairings
L-Arginine + L-Citrulline
L-Citrulline converts to arginine in the kidneys far more efficiently than oral arginine; the two share the same nitric oxide pathway.
Creatine + L-Citrulline
A popular pre-workout pairing: citrulline for blood flow and pumps, creatine for power and strength output.
Collagen + Vitamin C
Vitamin C is a required cofactor for the enzymes that build collagen, so adequate vitamin C supports both dietary collagen and the body's own production.
Iron + Vitamin C
Taken together, vitamin C can multiply the absorption of plant-based iron.