Cofactor

Magnesium and Vitamin B5 (Pantothenic Acid)

Magnesium supports the same stress-response and energy pathways that rely on CoA.

By the Vital Matrix Editorial TeamReviewed by the Vital Matrix Research TeamLast updated June 25, 2026

Designed to work as a pair

One is required for the other to do its job, so they belong together in a stack.

How to take them

Magnesium

Dose
200–400 mg elemental magnesium per day
Timing
Evening for sleep support; with food to reduce GI upset

Vitamin B5 (Pantothenic Acid)

Dose
5 mg RDA; 100–500 mg for adrenal/skin support
Timing
With meals

Frequently asked

Can you take Magnesium and Vitamin B5 (Pantothenic Acid) together?

Yes, they are commonly taken together. Magnesium supports the same stress-response and energy pathways that rely on CoA.

What's the best time to take Magnesium and Vitamin B5 (Pantothenic Acid)?

Around the same time works well. Magnesium: Evening for sleep support; with food to reduce GI upset. Vitamin B5 (Pantothenic Acid): With meals.

How do Magnesium and Vitamin B5 (Pantothenic Acid) interact?

Cofactor: Required for the other to do its job. Magnesium supports the same stress-response and energy pathways that rely on CoA.

Related pairings