Magnesium and Vitamin B3 (Niacin)
Magnesium supports many of the same mitochondrial and stress pathways as B3.
Magnesium
A master mineral involved in 300+ enzyme reactions.
Vitamin B3 (Niacin)
The NAD+ precursor that supports energy, cholesterol, and cellular repair.
Designed to work as a pair
One is required for the other to do its job, so they belong together in a stack.
How to take them
Magnesium
- Dose
- 200–400 mg elemental magnesium per day
- Timing
- Evening for sleep support; with food to reduce GI upset
Vitamin B3 (Niacin)
- Dose
- 14–16 mg RDA; 500–2,000 mg for lipid effects under medical supervision
- Timing
- With meals; take lipid-lowering doses at night
Frequently asked
Can you take Magnesium and Vitamin B3 (Niacin) together?
Yes, they are commonly taken together. Magnesium supports many of the same mitochondrial and stress pathways as B3.
What's the best time to take Magnesium and Vitamin B3 (Niacin)?
Around the same time works well. Magnesium: Evening for sleep support; with food to reduce GI upset. Vitamin B3 (Niacin): With meals; take lipid-lowering doses at night.
How do Magnesium and Vitamin B3 (Niacin) interact?
Cofactor: Required for the other to do its job. Magnesium supports many of the same mitochondrial and stress pathways as B3.
Related pairings
Glycine + Magnesium
A classic sleep stack: glycine lowers core body temperature while magnesium glycinate relaxes muscles and calms the nervous system.
Magnesium + Vitamin D3
Magnesium is required to convert vitamin D into its active form, so low magnesium blunts D3's benefits.
L-Arginine + Magnesium
Magnesium supports vascular smooth muscle relaxation alongside nitric oxide from arginine.
Ashwagandha + Magnesium
Commonly combined for stress relief and better sleep quality.